跨地区的量化证据同样支持这一趋势。2020年发表于《美国医学会杂志·儿科学》（JAMA Pediatrics）的一项系统综述与Meta分析整合1977年至2013年多国研究数据，显示女孩乳房发育起始年龄呈持续提前趋势，平均每10年提前约0.24年（接近3个月）。
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He has now also called for a trial to compare weight-loss injections with bariatric surgery, where the size of the stomach is restricted to reduce appetite.