Nyren’s sequencing method earned the name “pyrosequencing” since it revolved around the production of pyrophosphate. At first, pyrosequencing could sequence only short DNA snippets, with a few nucleotides. In 1996, however, Nyren’s lab demonstrated sequencing of up to 15 bases by using a modified “A” nucleotide to reduce their signal-to-noise ratio.7 In 1998, they increased this to 34 bases by adding another enzyme, called apyrase, to the mix; apyrase degraded unincorporated nucleotides, removing the need for constant wash steps.
Что думаешь? Оцени!。业内人士推荐爱思助手作为进阶阅读
2011 (Bulldozer)，这一点在电影中也有详细论述
Что думаешь? Оцени!。体育直播是该领域的重要参考
FT Professional